While many GUI toolkits require you to precisely place widgets in a window, using absolute positioning, GTK+ uses a different approach. Rather than specifying the position and size of each widget in the window, you can arrange your widgets in rows, columns, and/or tables. The size of your window can be determined automatically, based on the sizes of the widgets it contains. And the sizes of the widgets are, in turn, determined by the amount of text they contain, or the minimum and maximum sizes that you specify, and/or how you have requested that the available space should be shared between sets of widgets. You can perfect your layout by specifying padding distance and centering values for each of your widgets. GTK+ then uses all this information to resize and reposition everything sensibly and smoothly when the user manipulates the window.GTK+ arranges widgets hierarchically, using containers. They are invisible to the end user and are inserted into a window, or placed within each other to layout components. There are two flavours of containers: single-child containers, which are all descendants of Gtk.Bin, and multiple-child containers, which are descendants of Gtk.Container. The most commonly used are vertical or horizontal boxes (Gtk.Box) and grids (Gtk.Grid).

Source: 5. Layout Containers — Python GTK+ 3 Tutorial 3.4 documentation