Problem: The US Food and Drug Administration (FDA) and ISMP have received reports that describe errors associated with the wrong frequency of administration with mefloquine as well as wrong drug errors in which mefloquine was dispensed instead of the intended MALARONE (atovaquone/proguanil). Both mefloquine (previously marketed as LARIAM*) and Malarone are FDA approved for use in the treatment and prophylaxis of malaria, but they each have different dosing regimens (Table 1).

Source: FDA Advise-ERR: Mefloquine-Not the same as Malarone! | Institute For Safe Medication Practices